The Voxa Blade™ ultra-high-throughput imaging pipeline is customizable to provide complete industrial automation and scaling, transforming nanoscale electron-optical imaging from a manual platform producing exquisite but limited quantities of data to a rapid and effective process for charting the full nanoscale detail of our world. In much the same way that improved satellites enabled us to effortlessly map the full macro surface of our world, Blade automation increases image acquisition speed by as much as 1,000,000x over conventional manual workflows.